两性霉素B

Amphotericin B

产品编号： KS1013

CAS: 1397-89-3

分子量: 924.08

规格及纯度: USP级，750mg/g

分子式: C₄₇H₇₃NO₁₇

货号	产品规格	市场价	会员价	购物车
KS1013-1g	USP级，750mg/g	¥91.20	请登录	立即购买
KS1013-5g	USP级，750mg/g	¥366.70	请登录	立即购买
KS1013-25g	USP级，750mg/g	¥1103.90	请登录	立即购买
KS1013-100g	USP级，750mg/g	¥3642.30	请登录	立即购买

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中文名称	两性霉素B
中文别名	两性霉素B;二性霉素B;两性霉素;两性霉素乙;可溶性两性霉素 B;两性霉属B;庐山霉素;多烯抗生素;两性多烯;可溶性两性霉素;两性酶素b;两性霉素B EP标准品;两性霉素B USP标准品;两性霉素B 标准品;两性霉素B,BR;两性霉素B-13C6;两性霉素B峰鉴别 EP标准品;两性霉素B口服粉;两性霉素B微生物鉴定 EP标准品;两性霉素B（冷藏运输）;芦山霉素;两性霉素 B 来源于链霉菌属;异性霉素;两性霉素 B;两性霉素B(细胞培养级);两性霉素B溶液
英文名称	Amphotericin B
英文别名	Amphotericin B;33-[(3-amino-3,6-dideoxy-beta-d-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid;ABELCET;AMBISOME;AMPHOTERCIN B;AMPHOTERICIN B SOLUBILIZED;AMPHOTERICIN B, SOLUBLE;AMPHOTERICIN B, STREPTOMYCES NODOSUS;AMPHOTERICIN B, STREPTOMYCES SPECIES;AMPHOZONE;FUNGIZONE;FUNGIZONE(R);14,39-dioxabicyclo(33.3.1)nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carbo;33-((3-amino-3,6-dideoxy-beta-d-mannopyranosyl)oxy)-1,3,5,6,9,11,-xylicaci;amphomoronal;ampho-moronal;amphotericinbstandardsolution;amphotericineb;Amphotericin B trihydrate;Abelecet;Amphocin;AMPHOTERICIN B, NON STERILE;fungilin;Halizon;LNS-AmB;ns718;F;Amphotericine B;Amphotericin;Amfotericina B;Amphotericinum B;AMPH-B;Liposomal Amphotericin B;Amphotericin-B;Amphortericin B;Amphotec;Mysteclin-F;7XU7A7DROE;DSSTox_CID_2601;DSSTox_RID_76653;DSSTox_GSID_22601;Fungisome;Fungisone;Amphotericinum B [INN-Latin];Amfotericina B [INN-Spanish];Amphotericine B [INN-French];C47H73NO17;Anfotericine B;AMPHOTERICIN B [HSDB];AMPHOTERICIN B [JAN];Amphotericin B, Streptomyces nodosus;AMPHOTERICIN B [INN];Fungizone (TN);A01AB04;Amphotericin B [USP:INN:JAN];Q412223;NSC527017;Ambil;(1R-(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S))-33-((3-Amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo(33.3.1)nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid;Amphotericin BETA;J02AA01;LMPK06000002;UNII-7XU7A7DROE;14,39-DIOXABICYCLO(33.3.1)NONATRIACONTA-19,21,23,25,27,29,31-HEPTAENE-36-CARBOXYLIC ACID, 33-((3-AMINO-3,6-DIDEOXY-BETA-D-MANNOPYRANOSYL)OXY)-1,3,5,6,9,11,17,37-OCTAHYDROXY-15,16,18-TRIMETHYL-13-OXO-, (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S;SCHEMBL17973;Amphotericin B (USP:INN:JAN);Amphotec (TN);DTXCID802601;(1S,3R,4E,6E,8E,10E,12E,14E,16E,18S,19R,20R,21S,25R,27R,30R,31R,33S,35R,37S,38R)-3-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-19,25,27,30,31,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,12,14,16-heptaene-38-carboxylic acid;G01AA03;AMPHOTERICIN B [MI];Prestwick3_000410;Amphotericin B?;(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-he;Amphotericin b, liposome [WHO-DD];AB00513832_02;4UH;D00203;Amphotericin B from Streptomyces sp., Vetec(TM) reagent grade, BioReagent, suitable for cell culture, ~80%;IAB;CHEMBL267345;NCGC00090808-01;Amp B;AMPHOTERICINUM B [WHO-IP LATIN];Funganiline;AI3-26528;AMPHOTERICIN B (EP MONOGRAPH);14,39-Dioxabicycl...
CAS No.	1397-89-3
分子式	C₄₇H₇₃NO₁₇
分子量	924.08
密度	1.34
沸点	1140.365°C at 760 mmHg
水溶性	<0.1 g/100 mL at 21 ºC
存储条件	2-8℃，避光
用途	与真菌细胞膜的主要成分--ergosterol相关，破坏真菌的细胞膜结构，从而破坏真菌细胞，并导致真菌细胞的凋亡
注意	仅用于科学研究

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两性霉素B（Amphotericin B）是一种广谱抗真菌药物，通常用于治疗严重的真菌感染。它的主要作用是通过与真菌细胞膜的主要成分--ergosterol相关，破坏真菌的细胞膜结构，从而破坏真菌细胞，并导致真菌细胞的凋亡。

两性霉素B的主要用途包括：

1. 治疗真菌性血症：如念珠菌属、曲霉菌属等引起的血液感染。

2. 治疗真菌性脑膜炎：如念珠菌性脑膜炎等。

3. 治疗深部真菌感染：如念珠菌性感染、曲霉感染、组织胞浆菌病等。

4. 治疗其他真菌感染：如肺真菌感染、皮肤真菌感染等。

尽管两性霉素B是一种有效的药物，但由于其广谱性和毒性较高，使用时需特别小心。它通常供静脉注射而不被口服，因为它会导致一些严重的不良反应，比如肾脏损害、电解质失衡等。

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